About Miriam Sharpe
Science Communicator at the Department of Biochemistry, University of Otago.Cancer research in te reo Māori
After only two years into his journey to learn te reo Māori (the Māori language), PhD student Conor Vaessen has prepared a short cancer research talk entirely in his newly adopted language.
Conor is a PhD student in the Centre for Translational Cancer Research in the Department of Biochemistry, and is finding new drug treatments for hereditary stomach cancer.
He has kindly agreed to record his kōrero Māori (Māori talk) and have it posted on YouTube so that we can all learn about his mahi (work), both in reo Māori and in cancer research.
Conor prepared this talk for the School of Biomedical Sciences three minute research talks in Māori (ngā kōrero rangahau toru meneti) held in September in the Hunter Centre.
Unfortunately Conor was not able to attend on the day, but he has since presented the kōrero to the Department of Biochemistry where everyone was impressed by what many view as a daunting task. He has surely inspired others in the Department to kōrero Māori in their research!
Ka pai tō mahi, Conor. Ka mau te wehi! Great work. Awesome!
Diagnostic potential of CT-DNA
An article written by 300-level Biochemistry student Emily Crosse about research by PhD student Jordon Lima.
Circulating tumour DNA (ct-DNA), is cell-free DNA released from tumours into the bloodstream, with a short half-life, making it a good potential marker for easy detection of colorectal cancer in patients, via the bloodstream. Currently tissue biopsies are performed to identify cancer, however this is a difficult and invasive detection method, contributing to the lack of early diagnosis of colorectal cancer and challenges in therapeutic monitoring. Continue reading
Bringing lysosomes into the limelight: What happens when they don’t work and what are we doing to fix this?
An article written for The Sheet by 300-level Biochemistry student Rose Harper.
A groundbreaking gene therapy for the childhood neurodegenerative disorder Batten disease has been created by researchers in the Biochemistry department at the University of Otago, and they have not stopped there.
Seven students’ research adventures
We recently put up new posters outside the Biochemistry undergraduate laboratories to entertain the students as they wait for classes to start, and show them the kinds of things they could do if they continue their research adventures with the department.
Into introns?
Phylogenetic tree showing the widespread loss of introns during the evolution of fungi.
Genes within the DNA of humans, plants & yeasts are actually interrupted with bits of non-gene DNA scattered throughout, and these bits are called introns. Otago Biochemistry’s Associate Professor Chris Brown and Dr Chun Shen Lim delve into the evolution of an intriguing genetic phenomenon…
Continue reading
How to make life from scratch: Understanding molecules that organise themselves
300-level biochemistry student Hannah Gordon writes about the potential uses of cells that we design ourselves and the spontaneously organising molecules that we must understand before we can make artificial cells.
Can you imagine a self-assembling, low maintenance system that converts household waste into fuel to heat and power your home? Continue reading
Biochemistry – with colour! Or the day I narrowly avoided seaweed stain down my front (and found out about a really cool protein)
The red algae, Griffithsia sp.
Some time back, I was absent-mindedly striding down the particleboard-clad corridors of the Otago Biochemistry Department, when I nearly smacked right into Malcolm Rutledge, one of our excellent assistant research fellows. Luckily, I stopped just in time, because he was carrying very precious cargo. Nestled in a polystyrene box filled with ice, was a glass tube with a brilliant crimson-red liquid in it. Continue reading
Yes, viruses attack bacteria – and bacteria fight back, but not the way we thought
Lego model of a bacteriophage (image: Pascal, Heidelberg, Germany; licensed under CC BY 2.0)
Recent insights into how bacteria defend themselves against viruses, as revealed by Otago Biochemistry scientists and their colleagues, could guide the development of new treatments for bacterial infections. Continue reading
Kiwi and moa teach us about what makes species different
Paul Gardner and moa skeletons at the Otago Museum.
The kiwi, the emu, the moa, the cassowary, the rhea, the ostrich. They’re all part of a group of flightless birds from the Southern hemisphere known as ratites, and they’re giving us some very cool lessons on how animals evolve.
Otago Biochemistry’s Dr Paul Gardner and his bioinformatic colleagues from Harvard University, the Welcome Sanger Institute, and the Universities of Texas and Toronto have been using DNA sequences from these birds to figure out how species evolve, at the DNA level.
How viruses that kill bacteria can help in cancer research
Bacteriophage cluster around a bacterium, ready to hijack its resources. Image: Dr Graham Beards|Wikimedia.
Dr Adam Middleton, a researcher at Otago Biochemistry, introduces bacteriophage viruses and explains how he uses them to help with his research into molecules involved in cancer.
The bacteriophage – ‘the deadliest being on earth’ – is a virus that infects bacteria and forces the bugs to dedicate the remainder of their brief lives to generate more phage. Continue reading
