One of the amazing things your body does is to protect itself against disease. When bacteria or viruses invade your body, or you cut yourself, your white blood cells and the substances they produce will protect you, and start healing the damage. The affected area swells up and hurts. This process is called inflammation.
However, when something goes wrong and a body can’t turn off the inflammation response, or it turns on at the wrong time, inflammation can cause arthritis and other autoimmune diseases, and can even lead to cancer. Continue reading
Everywhere you look there’s something to stress you: Trump-induced stressing over the end of the world, working insane hours to gain a toe-hold on the housing ladder or to keep food on the table, kids screaming, keeping up with social media, etc…
It’s not just your body as a whole that has to deal with stress. Your cells do too. But what your cells consider to be stressful is probably not at the top of your list of things you worry about. Continue reading
We all know that eating too much bad food and not exercising puts us at risk of cardiovascular disease. But did you know there is another risk factor that increases the risk of heart disease in more than 1 in 5 people, that is determined by a person’s genetics, doesn’t respond to diet or exercise, and currently has no treatment?
This risk factor is a high level of lipoprotein(a) in the blood.
Lipoproteins are packages for carrying lipids (a fancy word for fats and oils) in the blood. Lipids do not mix well with water or blood, therefore they have to be packaged up with special proteins so they can be moved in the blood stream around the body. Continue reading
Wayne Patrick, a senior lecturer in the Otago Department of Biochemistry, is a devoted fan of evolution and proteins. He and his former PhD student, Matilda Newton, along with colleagues in Sweden, have been looking at changes that happen as an organism evolves, not just in the genes, but also in the machinery of cells, the proteins.
Thanks to Darwin and others we know a great deal about evolution, but there is still a lot to learn, particularly the nitty-gritty at the molecular level. We need to understand how evolution works, not just to understand how people and other creatures came into existence, but for many reasons, especially to improve our understanding and treatment of diseases. Continue reading