Professor Tony Blakely, Associate Professor Nick Wilson, Professor John Attia (University of Newcastle and Hunter Medical Research Institute, Australia)
Many observational studies suggest that moderate alcohol consumption reduces cardiovascular disease (CVD) risk. The so-called J-shaped curve. We summarised the ‘state of play’ on this topic at PHE Blog in early 2014. In the last few weeks a large ‘Mendelian randomisation’ study (like a genetically determined RCT of alcohol consumption – a study design with much potential for identifying causal (as opposed to confounded) associations) has been published suggesting that any alcohol consumption increases CVD. If true, this means the overall health harm from alcohol consumption in our society is even higher than currently thought. If so it would make cost-effective interventions such as alcohol taxation even more justified.