{"id":343,"date":"2022-05-08T04:57:56","date_gmt":"2022-05-07T16:57:56","guid":{"rendered":"https:\/\/blogs.otago.ac.nz\/keithgordon\/?p=343"},"modified":"2022-05-08T04:57:56","modified_gmt":"2022-05-07T16:57:56","slug":"new-publication-in-crystal-growth-and-design","status":"publish","type":"post","link":"https:\/\/blogs.otago.ac.nz\/keithgordon\/new-publication-in-crystal-growth-and-design\/","title":{"rendered":"New publication in Crystal Growth and Design"},"content":{"rendered":"<p>K\u0101rlis, Peter, Sara and Keith recently published a paper entitled &#8220;<span class=\"hlFld-Title\">Nondestructive Spatial Dehydration Analysis of Crystalline Hydrates in Pharmaceutical Solid Dosage Forms Using Spatially Offset Low-Frequency Raman Spectroscopy&#8221; in Crystal Growth and Design (<span class=\"cit-year-info\">2022)<\/span><span class=\"cit-volume\"> 22<\/span><span class=\"cit-pageRange\"> 2946\u20132953 <a href=\"https:\/\/doi.org\/10.1021\/acs.cgd.1c01401\">https:\/\/doi.org\/10.1021\/acs.cgd.1c01401.<\/a><\/span><br \/>\n<\/span><\/p>\n<p><a href=\"https:\/\/blogs.otago.ac.nz\/keithgordon\/files\/2022\/04\/Peter-Sara-Karlis-and-Keith.png\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-325\" src=\"https:\/\/blogs.otago.ac.nz\/keithgordon\/files\/2022\/04\/Peter-Sara-Karlis-and-Keith.png\" alt=\"\" width=\"1002\" height=\"256\" srcset=\"https:\/\/blogs.otago.ac.nz\/keithgordon\/files\/2022\/04\/Peter-Sara-Karlis-and-Keith.png 1002w, https:\/\/blogs.otago.ac.nz\/keithgordon\/files\/2022\/04\/Peter-Sara-Karlis-and-Keith-300x77.png 300w, https:\/\/blogs.otago.ac.nz\/keithgordon\/files\/2022\/04\/Peter-Sara-Karlis-and-Keith-768x196.png 768w, https:\/\/blogs.otago.ac.nz\/keithgordon\/files\/2022\/04\/Peter-Sara-Karlis-and-Keith-500x128.png 500w\" sizes=\"auto, (max-width: 1002px) 100vw, 1002px\" \/><\/a><\/p>\n<p><a href=\"https:\/\/blogs.otago.ac.nz\/keithgordon\/files\/2022\/05\/SOLFRS-citric.jpg\"><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-large wp-image-344\" src=\"https:\/\/blogs.otago.ac.nz\/keithgordon\/files\/2022\/05\/SOLFRS-citric-1024x358.jpg\" alt=\"\" width=\"1024\" height=\"358\" srcset=\"https:\/\/blogs.otago.ac.nz\/keithgordon\/files\/2022\/05\/SOLFRS-citric-1024x358.jpg 1024w, https:\/\/blogs.otago.ac.nz\/keithgordon\/files\/2022\/05\/SOLFRS-citric-300x105.jpg 300w, https:\/\/blogs.otago.ac.nz\/keithgordon\/files\/2022\/05\/SOLFRS-citric-768x268.jpg 768w, https:\/\/blogs.otago.ac.nz\/keithgordon\/files\/2022\/05\/SOLFRS-citric-1536x537.jpg 1536w, https:\/\/blogs.otago.ac.nz\/keithgordon\/files\/2022\/05\/SOLFRS-citric-2048x716.jpg 2048w, https:\/\/blogs.otago.ac.nz\/keithgordon\/files\/2022\/05\/SOLFRS-citric-500x175.jpg 500w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/><\/a><\/p>\n<p>The paper showcases the capabilities of <span class=\"hlFld-Title\">Spatially Offset Low-Frequency Raman Spectroscopy<\/span> (SOLFRS) in being able to examine subsurface layers in a tablet and observe dehydration of those subsurface layers.\u00a0 The spectra were analyzed using multivariate methods and mode assignments were provided via periodic boundary condition calculations.\u00a0 An interesting potential for examining tablet degradation without the need to split open the tablet or even remove it from its packaging.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>K\u0101rlis, Peter, Sara and Keith recently published a paper entitled &#8220;Nondestructive Spatial Dehydration Analysis of Crystalline Hydrates in Pharmaceutical Solid Dosage Forms Using Spatially Offset Low-Frequency Raman Spectroscopy&#8221; in Crystal Growth and Design (2022) 22 2946\u20132953 https:\/\/doi.org\/10.1021\/acs.cgd.1c01401. The paper showcases the capabilities of Spatially Offset Low-Frequency Raman Spectroscopy (SOLFRS) in being able to examine subsurface [&hellip;]<\/p>\n","protected":false},"author":33170,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[],"tags":[],"class_list":["post-343","post","type-post","status-publish","format-standard","hentry"],"_links":{"self":[{"href":"https:\/\/blogs.otago.ac.nz\/keithgordon\/wp-json\/wp\/v2\/posts\/343","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/blogs.otago.ac.nz\/keithgordon\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/blogs.otago.ac.nz\/keithgordon\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/blogs.otago.ac.nz\/keithgordon\/wp-json\/wp\/v2\/users\/33170"}],"replies":[{"embeddable":true,"href":"https:\/\/blogs.otago.ac.nz\/keithgordon\/wp-json\/wp\/v2\/comments?post=343"}],"version-history":[{"count":0,"href":"https:\/\/blogs.otago.ac.nz\/keithgordon\/wp-json\/wp\/v2\/posts\/343\/revisions"}],"wp:attachment":[{"href":"https:\/\/blogs.otago.ac.nz\/keithgordon\/wp-json\/wp\/v2\/media?parent=343"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/blogs.otago.ac.nz\/keithgordon\/wp-json\/wp\/v2\/categories?post=343"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/blogs.otago.ac.nz\/keithgordon\/wp-json\/wp\/v2\/tags?post=343"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}