Congratulations to Josh and Keith on their new paper in JACS (DOI: 10.1021/jacs.2c12605) with a team led by Paul Hume and Justin Hodgkiss. The paper describes how a combination of spectroscopy, calculations and synthesis of a series of compounds provides insight into the kinetics of intersystem crossing (ISC). ISC is an intrinsic exciton loss channel. The paper shows that conformational disorder is a key driver in facile ISC and delivers some key design criteria for efficient organic photovoltaics and light-emitting diodes.