{"id":9,"date":"2018-10-25T11:30:27","date_gmt":"2018-10-24T22:30:27","guid":{"rendered":"https:\/\/blogs.otago.ac.nz\/jamescrowley\/?page_id=9"},"modified":"2024-09-01T09:30:56","modified_gmt":"2024-08-31T21:30:56","slug":"research","status":"publish","type":"page","link":"https:\/\/blogs.otago.ac.nz\/jamescrowley\/research\/","title":{"rendered":"Research"},"content":{"rendered":"

Relevant Disciplines<\/strong><\/p>\n

Organic \/ Inorganic \/ Organometallic \/ Materials \/ Supramolecular Chemistry<\/p>\n

My research interests are in synthetic organic, inorganic, organometallic and supramolecular chemistry. I am interested in the design and synthesis of new functional materials.\u00a0I have expertise in a wide range of synthetic and spectroscopic techniques including NMR, IR, UV-vis and X-ray crystallography. Major areas of interest include:<\/p>\n

CuAAC \u201cClick\u201d coordination chemistry. <\/strong>The mild and modular Cu(I)-catalyzed 1,3-cycloaddition of terminal alkynes with organic azides (the CuAAC \u201cclick\u201d reaction) allows the ready formation of functionalised 1,4-disubstituted-1,2,3-triazole scaffolds and this has led to an explosion of interest in the coordination chemistry of these heterocycles. A diverse array of mono-, bi-, tri- and polydentate ligands incorporating 1,4-disubstituted-1,2,3-triazole units have been synthesised and characterised. Easy access to readily functionalised ligand architectures is of crucial importance in a range of different areas and we are exploiting these ligands for the development of new catalysts, metallo-pharmaceuticals, bio-imaging agents, metallosupramolecular architectures, and molecular machines.<\/p>\n

Functional metallosupramolecular architectures.<\/strong> I am also interested in the engineering of functional molecular architectures via self-assembly. We have recently developed a range of methods to heterometallic and multicavity metallosupramolecular architectures as part of efforts to enhance the applications of these systems.\u00a0 In particular we are attempting to exploit these self-assembled cages as novel metallo-pharmaceuticals, for drug delivery and as nanoreactors for carrying out chemical transformations.<\/p>\n

\"\"<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

Relevant Disciplines Organic \/ Inorganic \/ Organometallic \/ Materials \/ Supramolecular Chemistry My research interests are in synthetic organic, inorganic, organometallic and supramolecular chemistry. I am interested in the design and synthesis of new functional materials.\u00a0I have expertise in a wide range of synthetic and spectroscopic techniques including NMR, IR, UV-vis and X-ray crystallography. Major […]<\/p>\n","protected":false},"author":25465,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-9","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/blogs.otago.ac.nz\/jamescrowley\/wp-json\/wp\/v2\/pages\/9","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/blogs.otago.ac.nz\/jamescrowley\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/blogs.otago.ac.nz\/jamescrowley\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/blogs.otago.ac.nz\/jamescrowley\/wp-json\/wp\/v2\/users\/25465"}],"replies":[{"embeddable":true,"href":"https:\/\/blogs.otago.ac.nz\/jamescrowley\/wp-json\/wp\/v2\/comments?post=9"}],"version-history":[{"count":0,"href":"https:\/\/blogs.otago.ac.nz\/jamescrowley\/wp-json\/wp\/v2\/pages\/9\/revisions"}],"wp:attachment":[{"href":"https:\/\/blogs.otago.ac.nz\/jamescrowley\/wp-json\/wp\/v2\/media?parent=9"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}