Upcoming events hosted by or involving Genetics Otago will be listed here. Please check back regularly for updates. A calendar of events that may be of interest to our members can be found at the bottom of this page and in the sidebar of other pages on this site, please note that this includes events hosted outside of Genetics Otago.
VISG Seminar Series
The Virtual Institute of Statistical Genetics (VISG) Hub is a key part of Genetics Otago, providing a platform for researchers to collaborate and exchange knowledge and expertise in statistical genetics. The VISG Hub hosts seminars, workshops, and other events to promote statistical genetics research and foster collaboration between researchers.
We’re excited to announce our monthly genetics research seminars, aimed at connecting researchers in the field. The seminars will commence in May 2023 and will be hosted by GO’s Virtual Institute of Statistical Genetics (VISG) Hub along with the Department of Mathematics and Statistics at the University of Otago. These seminars will be available in person or via Zoom, and all are welcome.
Date: 3rd Thursday of the month
Time: 11:00 am – 12:00 pm
Schedule
- May: Associate Professor Phil Wilcox, University of Otago
- June: Professor Mik Black, University of Otago
- July: Dr Ludovic Dutoit, University of Otago – please note that this seminar will be held on the 27th of July rather than the 20th due to ICG.
- August: Dr Setegn Alemu, AgResearch
- September: Ee Cheng Oi, Abacus Bio
- October: Franziska Weik, Beef + Lamb NZ Genetics – Cancelled
- November: Dr Jane Symonds and Dr Megan Scholtens, Cawthron – please note that this seminar will be held on the 17th of November rather than the 16th due to the Genetics Otago Annual Symposium.
Zoom Details
If you would like the Zoom details for this event, please contact us.
Next Seminar
The next seminar will be held on Friday the 17th of November, 11 am in Biochemistry Seminar Room G13 and will be given by Dr Jane Symonds and Dr Megan Scholtens, Cawthron Institute.
Title: Environmental resilience in aquatic species
Abstract: The New Zealand aquaculture sector faces growing vulnerability due to climate change, with marine heatwaves already causing elevated summer mortality rates in Greenshell mussels and king (Chinook) salmon. To tackle these challenges, selective breeding and genomic selection offer long-term solutions. Temperature challenge models, implemented in controlled tank environments, have been developed for both species. So far, this approach has been applied successfully to test more than 230 pedigree king salmon families and 21 Greenshell mussel families. Heritabilities for time to death at elevated temperature were high (0.34 to 0.48) suggesting that selection for improved thermotolerance is possible.
Megan Scholtens
Megan is a geneticist within the Aquaculture Group at Cawthron and is involved in a number of research projects across the ‘Shellfish Aquaculture’ and ‘Finfish Climate Change Adaptation’ platforms. Megan specialises in the application of genetic and genomic methodologies to enhance the understanding of how genes affect traits such as growth, development, behaviour, reproduction and immunity to improve the efficiency, resilience and survivability of aquatic species. In addition, Megan contributes to research activities of the Aquaculture team by integrating the experimental biology with commercial production to help provide solutions for clients and deliver tangible outcomes for the aquaculture industry.
Jane Symonds
Jane is a Senior Scientist and Team Leader in the Aquaculture Group at Cawthron. Jane’s focus is the application of research to enhance sustainable commercial production with a specific interest in king salmon farming and selective breeding. She has over 30 years of experience in this field. As a science programme leader she oversees a wide range of multi-disciplinary collaborative projects with internal and external partners, including salmon feed efficiency, genomics, behaviour, health, physiology, microbiomics, climate change adaptation, data science and developing trials to selectively breed resilient and efficient king salmon. Implementation of research for sustainable and profitable aquaculture development is a key driver for Jane. Dr Symonds is also a Senior Adjunct Researcher at the University of Tasmania and helps supervise multiple post-graduate students.
If you have any questions about this seminar series please contact us.
Calendar of Events
The below is a calendar of events hosted by GO as well as events hosted by others that may be of interest to our members. If you have an event you would like us to include please contact us here.
Professor Julia Horsfield
Department of Pathology, University of Otago
‘Cohesin mutations are synthetic lethal with stimulation of WNT signaling’
Mutations in genes encoding subunits of the cohesin complex are common in several cancers, but may also expose druggable vulnerabilities. We generated isogenic MCF10A cell lines with deletion mutations of genes encoding cohesin subunits SMC3, RAD21 and STAG2 and screened for synthetic lethality with 3,009 FDA-approved compounds. The screen identified several compounds that interfere with transcription, DNA damage repair and the cell cycle. Unexpectedly, one of the top ‘hits’ was a GSK3 inhibitor, an agonist of Wnt signaling. We show that sensitivity to GSK3 inhibition is likely due to stabilisation of b-catenin in cohesin mutant cells, and that Wnt-responsive gene expression is highly sensitized in STAG2-mutant CMK leukemia cells. Moreover, Wnt activity is enhanced in zebrafish mutant for cohesin subunit rad21. Our results suggest that cohesin mutations could progress oncogenesis by enhancing Wnt signaling, and that targeting the Wnt pathway may represent a novel therapeutic strategy for cohesin mutant cancers.
Zoom Link:
https://otago.zoom.us/j/96479355495?pwd=RVR3L2NKb2RHZVM0TVE0QW96aFJpdz09#success
Password: 879963
Every little thing she does is magic: How our mother’s health affects our own
About Professor Jasoni’s research
When a mother is unwell during pregnancy, her offspring have increased lifelong risk for neurological disease. Christine’s research interest is in how the brain forms before we are born, with a particular focus on understanding how a mother’s health during this critical period of life can impact the unborn baby’s brain; and increase neurological disease risk.
Her group’s work has been published in some of the top international journals, and her trainees have gone on to prestigious positions nationally and abroad. Christine’s laboratory is situated in the Centre for Neuroendocrinology, among a group of researchers who are world-leaders in discovering how the brain controls some of our most essential bodily functions. Christine’s reach into the neuroscience community at Otago, however, is much broader. She is the Director of the 300-researcher-strong Brain Health Research Centre, is a former Director of the Neuroscience Degree Programme, and has won numerous awards for her neuroscience teaching.
This lecture will be followed by light refreshments, tea, coffee & juice.
Streaming information for Professor Christine Jasoni’s IPL
This event will be live-streamed, from 5:25pm Monday 5 October 2020, at the following web address:
Professor Christine Jasoni’s IPL video stream
Test your connection to the streaming service here:
Test Stream
Please note: Live streaming does not work with Internet Explorer.
John Smaillie Tennant Lecture on Wednesday, 7 October 2020 featuring Associate Professor David Orlovich from the Department of Botany. He will give his lecture on “The evolution of truffle-like fungi”.
See attached poster for more details
Tennant Lecture DAO 7.10.2020
PhD Student Presentations
Sai Shyam
“Developing circulating tumour cells as a model to identify tumour-specific epigenetic signatures of colorectal cancer metastasis”
Ben Halliday
“Building a Brain – From Phenotypes to Genes, and Back Again”
More details here:
200731 PSS_Sai & Ben
The Pathology Seminar Series continues this week with Dr Mihnea Bostina from Microbiology & Immunology. Dr Bostina will present a seminar entitled “Senecavirus: A Picornavirus with Potent Oncolytic Activity” in the D’Ath Lecture Theatre at 1pm this Friday – see attached for more information.
12:00 Noon, Monday, 2nd November
Room 208, 2nd Floor
Microbiology Building
720 Cumberland St
Ben Te Aika
Vision Matakuranga Co-Ordinator, Genomics Aotearoa,
‘Indigenous (Māori) Ethics’
The workshop will look to increase understanding of Matauraka Maori or Māori knowledge and knowledge systems in relation to science, Māori relationships with data and indigenous data derived works. Consultation from a practice point of view leading to improved engagement and outcomes. Understanding a key ethical expression of Taa Koha – an exchange of trust based responsibility and how this requires transparency, communication and mutual trust. Data sovereignty is an expression of Māori control, derived from territorial authority or Mana Whenua which is grounded in the Treaty of Waitangi.
The joint winners of the 2020 Rowheath Trust Award and Carl Smith Research Medal Lecture Dr Louise Bicknell and Associate Professor Anne-Marie Jackson will present their talks at 5:30pm on Tuesday 3 November in Burns 1 Lecture Theatre.
Dr Bicknell, from the Department of Pathology, will present her talk “The genetics of how we grow”
Our genetic code contains the key instructions on how our bodies and brain grow – yet we still don’t fully understand what mechanisms are involved. Dr Bicknell harnesses the power of rare genetic disorders, where people have restricted body or brain growth, to gain insight into these essential instructions. She will present her laboratory’s research efforts to understand the genetic control of growth and to help people affected by such disorders.
She will be followed by Associate Professor Anne-Marie Jackson (Ngāti Whātua, Ngāpuhi, Ngāti Kahu o Whangaroa, Ngāti Wai) who is co-Director of Te Koronga based in the Division of Sciences, School of Physical Education, Sport and Exercise Sciences. Her research focuses on mauri ora (flourishing wellbeing).
He kairangahau Māori o te rōpū rangahau o Te Koronga i roto i te Rohe a Ahikāroa, Te Kura Parawhakawai a Ahorangi Tuarua Anne-Marie Jackson (Ngāti Whātua, Ngāpuhi, Ngāti Kahu o Whangaroa, Ngāti Wai). Ko mauri ora te kaupapa o tōna mahi rangahau.
Associate Professor Jackson’s talk is titled ”Tēnei tātou Te Koronga: Indigenising the academy since mai rā anō”
The phrase Te Koronga is borrowed from the opening line of an ancient Māori chant that refers to a yearning for excellence. This is the research kaupapa she co-leads. In this kōrero, she will describe the dual parts of her role as a kaupapa Māori researcher. Firstly, she will outline her research expertise in Māori physical education and health which is the study and application of te ao Māori (Māori worldview), Te Tiriti (Treaty of Waitangi) and Kaupapa Māori for mauri ora (flourishing wellness). Secondly, she will discuss how through this disciplinary platform, as servants to our communities, we engage in transforming and indigenising the academy to ensure we as Māori are the critics and conscience of our society.
Nō te rerenga kōrero tuatahi o tētahi karakia tāwhito te rerenga kupu o te koronga. Ko te hiahia mō te hiranga te whakamārama o taua rerenga kupu. Nā Anne-Marie Jackson tētahi o ngā kaihautū o taua kaupapa rangahau. I roto i tēnei kōrero, ka kōrero a Anne-Marie ki ngā mea e rua e pā ana ki ōna mahi o te kairangahau kaupapa Māori. Tuatahi, ka whakarāpopoto ia i ōna mahi rangahau o te whakatinanahia o te hauora Māori, arā, ko te whakaritenga o te ao Māori, Te Tiriti me te Kaupapa Māori mō te mauri ora. Tuarua, ka kōrero ia e pā ana ki te mahi o te rangahau, mā te rangahau ngā hapori e hāpai, mā te rangahau anō mātou e panoni, e whakamāori hoki ngā whare wānanga kia ū ki te kaupapa matua, he kaiwhakamana mātou mō tō mātou ao whānui.
The Carl Smith Research medal is one of the University’s highest research honours, and awarded annually to recognise the outstanding research performance of early career staff.
This is a free public lecture and all are welcome to attend and learn.
We have a special seminar from Dr Jane MacDonald and colleagues based at the Centre for Women’s Health Research, Wellington Faculty of Health, Victoria University of Wellington. They will present ‘He Tapu Te Whare Tangata (the sacred house of humanity)’, a randomised controlled trial of self-testing for HPV infection in Māori women.
Please see attached for more information.He tapu te whare tangata_poster
The OMSRS Masters and Honours Student Speaker awards, and Annual General Meeting will be held on 4th November 2020 at 5pm in the Barnett Lecture Theatre.
10 speakers have been selected from a range of departments. A prize of $500 will be awarded for the best presentation, and a prize of $250 will be awarded to the runner up.
We will also hold a brief Annual General Meeting during the break, and announce the winner and runners up of our annual Science Writing Prize, sponsored by Kainic Medical Communications.
Approximate timings are given below.
Departmental seminar series continues with Dr Xochitl Morgan from Microbiology & Immunology. Her seminar is entitled ‘Understanding ecosystem dysfunction in inflammatory bowel disease’.
Please see attached for more information: Morgan_poster
