{"id":396,"date":"2026-04-13T11:58:57","date_gmt":"2026-04-12T23:58:57","guid":{"rendered":"https:\/\/blogs.otago.ac.nz\/fellner\/?p=396"},"modified":"2026-04-13T11:59:53","modified_gmt":"2026-04-12T23:59:53","slug":"bioorganic-chemistry-paper-on-carbamoyl-fluoride-inhibitors-published","status":"publish","type":"post","link":"https:\/\/blogs.otago.ac.nz\/fellner\/bioorganic-chemistry-paper-on-carbamoyl-fluoride-inhibitors-published\/","title":{"rendered":"Bioorganic Chemistry paper on carbamoyl fluoride inhibitors published"},"content":{"rendered":"\n<p class=\"wp-block-paragraph\">Our latest publication &#8220;Carbamoyl fluorides as serine hydrolase inhibitors: a case study on FphI from <em>Staphylococcus aureus.<\/em>&#8221; is now online at <a href=\"https:\/\/doi.org\/10.1016\/j.bioorg.2026.109834\" target=\"_blank\" rel=\"noreferrer noopener\">10.1016\/j.bioorg.2026.109834<\/a><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Exactly two years from cold email contact to joint publication between Otago and University of Ljubljana<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">First Email Wednesday, April 3, 2024 &amp; published: Available online 3 April 2026<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">The group at Ljubljana is developing a new class of serine hydrolase inhibitors based on a carbamoyl fluoride warhead and we were working on the perfect test enzyme to demonstrate their potential in FphI from <em>S. aureus<\/em>. Driven by George Randall and An\u017ee Meden who share first authorship it all came together quickly and very well. Also a big thank you to all the other involved co-authors. We are looking forward to expanding the collaborations in this area to many other projects.<\/p>\n\n\n\n<figure class=\"wp-block-image size-large\"><a href=\"https:\/\/blogs.otago.ac.nz\/fellner\/files\/2026\/04\/1-s2.0-S0045206826003706-ga1_lrg.jpg\"><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"306\" src=\"https:\/\/blogs.otago.ac.nz\/fellner\/files\/2026\/04\/1-s2.0-S0045206826003706-ga1_lrg-1024x306.jpg\" alt=\"\" class=\"wp-image-399\" srcset=\"https:\/\/blogs.otago.ac.nz\/fellner\/files\/2026\/04\/1-s2.0-S0045206826003706-ga1_lrg-1024x306.jpg 1024w, https:\/\/blogs.otago.ac.nz\/fellner\/files\/2026\/04\/1-s2.0-S0045206826003706-ga1_lrg-300x90.jpg 300w, https:\/\/blogs.otago.ac.nz\/fellner\/files\/2026\/04\/1-s2.0-S0045206826003706-ga1_lrg-768x230.jpg 768w, https:\/\/blogs.otago.ac.nz\/fellner\/files\/2026\/04\/1-s2.0-S0045206826003706-ga1_lrg-1536x459.jpg 1536w, https:\/\/blogs.otago.ac.nz\/fellner\/files\/2026\/04\/1-s2.0-S0045206826003706-ga1_lrg-2048x613.jpg 2048w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/><\/a><\/figure>\n","protected":false},"excerpt":{"rendered":"<p>Our latest publication &#8220;Carbamoyl fluorides as serine hydrolase inhibitors: a case study on FphI from Staphylococcus aureus.&#8221; is now online at 10.1016\/j.bioorg.2026.109834 Exactly two years from cold email contact to joint publication between Otago and University of Ljubljana First Email Wednesday, April 3, 2024 &amp; published: Available online 3 April 2026 The group at Ljubljana [&hellip;]<\/p>\n","protected":false},"author":40025,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[],"tags":[],"class_list":["post-396","post","type-post","status-publish","format-standard","hentry"],"_links":{"self":[{"href":"https:\/\/blogs.otago.ac.nz\/fellner\/wp-json\/wp\/v2\/posts\/396","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/blogs.otago.ac.nz\/fellner\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/blogs.otago.ac.nz\/fellner\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/blogs.otago.ac.nz\/fellner\/wp-json\/wp\/v2\/users\/40025"}],"replies":[{"embeddable":true,"href":"https:\/\/blogs.otago.ac.nz\/fellner\/wp-json\/wp\/v2\/comments?post=396"}],"version-history":[{"count":0,"href":"https:\/\/blogs.otago.ac.nz\/fellner\/wp-json\/wp\/v2\/posts\/396\/revisions"}],"wp:attachment":[{"href":"https:\/\/blogs.otago.ac.nz\/fellner\/wp-json\/wp\/v2\/media?parent=396"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/blogs.otago.ac.nz\/fellner\/wp-json\/wp\/v2\/categories?post=396"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/blogs.otago.ac.nz\/fellner\/wp-json\/wp\/v2\/tags?post=396"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}